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Welcome
to
Professor Ming Du
Group
Website
Our main focus is on
MALT lymphoma, which is solid tumors that originate from
cancerous growth of immune cells that are recruited to secretory
tissue such as the gastrointestinal tract, salivary glands, lung
and the thyroid gland.
The group's other
interests are research into cancer-causing viral proteins such
as Kaposi's sarcoma-associated herpesvirus (KSHV), Epstein-Barr
virus (EBV) and their role in cancers such as lymphomas such as PEL
and MCD.
By gaining insight into the mechanisms that underlie cancers, we can
better understand cancer immunity and viral oncogenesis.
The group has used both
aCGH and cDNA expression microarray to study the molecular
pathogenesis of lymphomas such as MALT, PEL, FL, MCL, DLBL and SMZL.
To this end the group have produced novel in house bioinformatics
software for the storage, management and analysis of data generated
from microarray and genomic applications.
The group has also
setup molecular diagnostic service for pathologists in the Norfolk
area. The molecular diagnostic service is now used routinely by
pathologists to help them in diagnosing cases using clonality
analysis, interphase FISH and EBER in situ hybridisation.
More details
regarding research and other activities from Prof Du's group will
appear later on on this website.
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